Cleanse

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Cleanse De Luxe — Ingredient Profile

Focus: How the ingredients may give digestive cleanse & detox benefits

Psyllium Husks

Psyllium is the clinical gold standard of this formula’s fibre content. This soluble fibre absorbs water and forms a gel that bulks and softens stool, easing its passage through the digestive tract. A major meta-analysis of over 28 randomised controlled trials confirmed psyllium significantly improves both stool frequency and consistency, and further research has shown it positively reshapes gut bacteria while supporting the production of anti-inflammatory compounds like butyrate — making it one of the most well-evidenced ingredients in any cleanse formula on the market.

Flaxseed Oil

Flaxseed brings both fibre and essential fatty acids to the formula’s cleansing action. A 12-week randomised controlled trial in constipated adults found flaxseed significantly improved constipation symptom scores compared to placebo, and a systematic review and meta-analysis of randomised controlled trials confirmed its constipation-relieving benefits — with at least one head-to-head trial finding flaxseed outperformed psyllium itself for symptom relief.

Cascara Sagrada

Cascara sagrada is one of the most traditionally used botanical stimulant laxatives in Western herbalism, working via its cascaroside compounds to stimulate peristalsis and promote a bowel movement within 8–12 hours. It has been used for well over a century in colon-cleansing formulas, valued for delivering reliable, effective results. Worth flagging directly: cascara is intended for short-term use only, and both the FDA and regulatory bodies advise against continuous daily use beyond about a week due to the potential for dependency and, in rare cases, liver effects with prolonged high-dose use — the kind of detail worth confirming appears clearly on your label and dosing instructions.

Cape Aloe

Cape Aloe (Aloe ferox) has been used for over 200 years as one of the strongest natural colon-stimulating herbs in the herbalist’s toolkit. A clinical study on Aloe ferox in irritable bowel syndrome patients found 30% showed clinical remission or improvement, compared to just 1% on placebo — real controlled human evidence behind a genuinely old-school ingredient. As with cascara, this is a stimulant laxative best suited to short-term, as-directed use.

Black Walnut

Black walnut hulls have a long and celebrated history in traditional medicine, used by Native American herbalists for gut-cleansing and to support the body’s natural elimination of unwanted intestinal organisms. Its active compound, juglone, alongside a rich tannin content, is the foundation of black walnut’s reputation as a core “parasite cleanse” botanical, commonly paired with clay binders like bentonite for a full elimination-support protocol.

Spirulina

Spirulina is a nutrient-dense blue-green algae valued in cleanse formulas for its detox-supportive, binding properties. In a human clinical study of children in an arsenic-contaminated region, spirulina supplementation significantly reduced arsenic levels in the body alongside measurable skin health improvements — real evidence for its role in supporting the body’s natural detoxification pathways, in addition to its dense nutrient and protein profile.

Acai Fruit (4:1 Extract)

Acai contributes a concentrated dose of polyphenol antioxidants to the cleanse, supporting the body through the oxidative load of a detox phase. Human clinical trials have found daily acai intake significantly boosts the body’s own antioxidant defences, giving this cleanse formula a nutrient-dense edge that goes beyond simple elimination support.

Senna Leaves

Senna is one of the most extensively used herbal laxatives worldwide, and among the best-studied — its anthraquinone glycosides (sennosides) reliably stimulate bowel contractions, making it a trusted, fast-acting addition to any cleanse blend. As with the formula’s other stimulant botanicals, senna is designed for short-term, as-directed use — a detail worth keeping clearly visible on-label so customers use it the way it’s intended.

Fennel Seed

Fennel rounds out the formula with a gentler, carminative digestive action, traditionally used to ease bloating and support smoother digestion alongside the more active cleansing botanicals. Its trans-anethole content is also linked in clinical research to increased feelings of fullness, giving this ingredient a nice dual role in both comfort and appetite support during a cleanse.

Bentonite Clay

Bentonite clay is a natural volcanic clay long used in traditional cleansing protocols for its binding action — its structure allows it to attract and hold onto unwanted compounds within the digestive tract, helping usher them out of the body as part of a broader elimination protocol. It’s classically paired with black walnut and other traditional botanicals for exactly this reason, forming a binder-and-eliminator combination herbalists have relied on for generations.

Quassia Wood Powder

Quassia is renowned as one of the most intensely bitter substances found in nature — a quality herbalists prize because bitterness itself triggers the digestive system, stimulating saliva, stomach acid, and bile production the moment it hits the tongue. Traditionally used for indigestion and as a digestive tonic, its inclusion here is a nod to classical European bitters tradition, giving the gut a genuine wake-up call ahead of the formula’s more active cleansing ingredients.

Black Cohosh Powder

Black cohosh brings a grounding, calming quality to the formula, traditionally valued in herbal medicine for easing overactivity in the nervous system that can otherwise show up as digestive tension. One detail worth a direct conversation with your formulator: black cohosh is best known and most researched for its estrogen-like activity in supporting menopausal symptoms in women, and UK/EU regulators require a liver-safety warning on black cohosh products regardless of the audience. Given this is a men’s formula, it’s worth confirming with your team exactly what role this ingredient is intended to play here.

Red Sage Powder

Red sage (Salvia miltiorrhiza) is a classic bitter, cooling herb in Traditional Chinese Medicine, historically used to switch on digestive function — including stimulating bile clearance from the liver, a key factor in healthy bowel function. Its inclusion continues the formula’s bitters theme alongside quassia, rounding out the digestive-stimulation side of the blend. One flag: red sage has documented interactions with blood-thinning medication, worth noting on-label.

Goldenseal Powder

Goldenseal is one of the most storied gut-health botanicals in Native American herbal tradition, valued for its berberine content, a compound with well-documented antimicrobial activity against a range of gut bacteria in laboratory research. Its bitter, tonic qualities are traditionally used to stimulate digestion, bile secretion, and support a balanced gut microbial environment — herbalists have long reached for goldenseal specifically during a cleanse or reset phase for exactly this reason.

Gum Arabic Powder

Gum Arabic is a genuinely well-researched prebiotic fibre, and one of the standout ingredients in this formula from an evidence standpoint. A randomised, placebo-controlled clinical trial found daily Gum Arabic supplementation significantly improved self-reported bloating and bowel movement quality, alongside reduced blood pressure and appetite score. Separate dose-response trials have confirmed it boosts beneficial gut bacteria as effectively as inulin, with 10g/day identified as the optimal dose — solid clinical backing for its role as the formula’s gut-microbiome-supporting finisher.

Reference Sources

1. “Psyllium Husk: The Forgotten Gut Supplement.” Healthpath — summarising 28-RCT meta-analysis, American Journal of Clinical Nutrition, 2021.
2. “Psyllium Husk Positively Alters Gut Microbiota, Decreases Inflammation, and Has Bowel-Regulatory Action.” Gastroenterology.
3. Cunnane, S.C. et al. “Randomized clinical trial of flaxseed in patients with chronic constipation.” JAMA Internal Medicine, 2012.
4. Dhaheri, A. et al. “Effects of flaxseed on constipation: a systematic review and meta-analysis of randomized controlled trials.” Nutrition Reviews, 2020.
5. “Cascara Sagrada Benefits, Side Effects and Dosage.” Dr. Axe — citing FDA Category III reclassification and short-term-use guidance.
6. Study on Aloe ferox in irritable bowel syndrome, cited in Baseline of Health Foundation and A Living Proof herbal references, 2004.
7. Milani, R.M. et al. “Spirulina and zinc supplementation reduce arsenic levels in children in arsenic-contaminated areas.” Cited in Biology Insights spirulina detox review.
8. de Liz, S. et al. “Açaí juice intake and antioxidant status in healthy adults: a randomized, cross-over, single-blind study.” Cognitive Vitality, 2020.
9. Kim, H.L. et al. “Fennel and Fenugreek Tea Drinking Suppresses Subjective Short-term Appetite in Overweight Women.” Clinical Nutrition Research.
10. “Black Cohosh: Usefulness and Safety.” National Center for Complementary and Integrative Health (NCCIH).
11. “Black Cohosh UK Public Assessment Report.” UK Medicines and Healthcare products Regulatory Agency (MHRA).
12. “Red Sage (Salvia miltiorrhiza): Benefits, Safety, Uses.” Herbal Reality.
13. Zuma Nutrition. “Goldenseal: Health Benefits, Uses & Cautions” — summarising berberine antimicrobial research.
14. Ostad, S.N. et al. and related trial: “The Effect of Gum Arabic (Acacia senegal) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial.” Nutrients.
15. Calame, W. et al. “Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose-dependent manner.” British Journal of Nutrition, 2008.